Version 5.4
Mus musculus Protein: Lamb3
Summary
InnateDB Protein IDBP-209167.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lamb3
Protein Name laminin, beta 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000016315
InnateDB Gene IDBG-209165 (Lamb3)
Protein Structure
UniProt Annotation
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Subcellular Localization Secreted, extracellular space, extracellular matrix, basement membrane.
Disease Associations
Tissue Specificity Found in the basement membranes (major component).
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032403 protein complex binding
Biological Process
GO:0007155 cell adhesion
GO:0050873 brown fat cell differentiation
Cellular Component
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005610 laminin-5 complex
Protein Structure and Domains
PDB ID MGI:99915
InterPro IPR000742 Epidermal growth factor-like domain
IPR002049 EGF-like, laminin
IPR008211 Laminin, N-terminal
IPR008979 Galactose-binding domain-like
PFAM PF00008
PF00053
PF00055
PRINTS
PIRSF
SMART SM00181
SM00180
SM00136
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q61087
PhosphoSite PhosphoSite-Q61087
TrEMBL
UniProt Splice Variant
Entrez Gene 16780
UniGene Mm.435441
RefSeq NP_032510
MGI ID
MGI Symbol Lamb3
OMIM
CCDS CCDS15637
HPRD
IMGT
EMBL AK155769 BC008516 CH466555 U43298
GenPept AAA85255 AAH08516 BAE33428 EDL12945 EDL12946

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca