InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il21r

Summary

InnateDB Protein

IDBP-209302.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il21r

Protein Name

interleukin 21 receptor

Synonyms

NILR;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033000

InnateDB Gene

IDBG-209298 (Il21r)

Protein Structure

UniProt Annotation

Function

This is a receptor for interleukin-21.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004896	cytokine receptor activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0019221	cytokine-mediated signaling pathway

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1890475

InterPro

IPR003961 Fibronectin, type III

PFAM

PF00041
PF01108

PRINTS

PIRSF

SMART

SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9JHX3

PhosphoSite

PhosphoSite-Q9JHX3

TrEMBL

Q3TAI3

UniProt Splice Variant

Entrez Gene

60504

UniGene

RefSeq

NP_068687

MGI ID

MGI Symbol

Il21r

OMIM

CCDS

CCDS21823

HPRD

IMGT

EMBL

AB049137 AF254068 AF269134 AF279436 AF477982 AF477983 AF477984 AF477985 AF477986 AK171826 CH466531

GenPept

AAF86350 AAG23420 AAG29347 AAL82632 AAL82633 AAL82634 AAL82635 AAL82636 BAB13736 BAE42685 EDL17327