InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Apmap

Summary

InnateDB Protein

IDBP-209310.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Apmap

Protein Name

RIKEN cDNA 2310001A20 gene

Synonyms

2310001A20Rik; AI314817;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000040840

InnateDB Gene

IDBG-209306 (Apmap)

Protein Structure

UniProt Annotation

Function

Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate (By similarity). May play a role in adipocyte differentiation. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Strongly expressed in adipose tissue. Highly expressed in liver, heart, and kidney. Expressed at intermediate level in brain and lung. Weakly expressed in spleen, skeletal muscle and testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004064	arylesterase activity
GO:0016844	strictosidine synthase activity

Biological Process

GO:0009058

biosynthetic process

Cellular Component

GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1919131

InterPro

IPR013658 SMP-30/Gluconolactonase/LRE-like region
IPR018119 Strictosidine synthase, conserved region

PFAM

PF08450
PF03088

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D7N9

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

71881

UniGene

Mm.414124

RefSeq

NP_082253

MGI ID

MGI Symbol

Apmap

OMIM

CCDS

CCDS16858

HPRD

IMGT

EMBL

AJ310638 AK009057 AK154266 AL845174 BC055706 CH466519

GenPept

AAH55706 BAB26050 BAE32477 CAC83967 CAM15679 EDL28569