Version 5.4
Mus musculus Protein: Hils1
Summary
InnateDB Protein IDBP-209371.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hils1
Protein Name histone H1-like protein in spermatids 1
Synonyms TISP64;
Species Mus musculus
Ensembl Protein ENSMUSP00000039866
InnateDB Gene IDBG-209369 (Hils1)
Protein Structure
UniProt Annotation
Function DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa.
Subcellular Localization Nucleus {ECO:0000269PubMed:14636221}. Chromosome {ECO:0000269PubMed:14636221}.
Disease Associations
Tissue Specificity Expressed exclusively in the testis by haploid germ cells (at protein level). {ECO:0000269PubMed:14636221}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0016568 chromatin modification
GO:0030154 cell differentiation
GO:0030261 chromosome condensation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
Protein Structure and Domains
PDB ID MGI:2136691
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QYL0
PhosphoSite PhosphoSite-Q9QYL0
TrEMBL Q5SWB1
UniProt Splice Variant
Entrez Gene 54388
UniGene
RefSeq NP_061262
MGI ID
MGI Symbol Hils1
OMIM
CCDS CCDS25267
HPRD
IMGT
EMBL AB022320 AB045724 AK005718 AY286319 BC061119 CH466556 JQ914238 JQ914240 JQ914241 JQ914242 JQ914243 JQ914244 JQ914245 JQ914246 JQ914247 JQ914248 JQ914251 JQ914252 JQ914253 JQ914254 JQ914255 JQ914258 JQ914259 JQ914260 JQ914261 JQ914262 JQ914263 JQ914264 JQ914265 JQ914266 JQ914267
GenPept AAH61119 AAQ23051 AFM97380 AFM97382 AFM97383 AFM97384 AFM97385 AFM97386 AFM97387 AFM97388 AFM97389 AFM97390 AFM97393 AFM97394 AFM97395 AFM97396 AFM97397 AFM97400 AFM97401 AFM97402 AFM97403 AFM97404 AFM97405 AFM97406 AFM97407 AFM97408 AFM97409 BAA82785 BAB24203 BAB97206 EDL15960

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca