Version 5.4
Mus musculus Protein: Pygb
Summary
InnateDB Protein IDBP-209374.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pygb
Protein Name brain glycogen phosphorylase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000035743
InnateDB Gene IDBG-209372 (Pygb)
Protein Structure
UniProt Annotation
Function Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004645 phosphorylase activity
GO:0008184 glycogen phosphorylase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:97828
InterPro IPR000811 Glycosyl transferase, family 35
IPR011833 Glycogen/starch/alpha-glucan phosphorylase
PFAM PF00343
PRINTS
PIRSF PIRSF000460
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CI94
PhosphoSite PhosphoSite-Q8CI94
TrEMBL Q3UZL2
UniProt Splice Variant
Entrez Gene 110078
UniGene Mm.222584
RefSeq NP_722476
MGI ID
MGI Symbol Pygb
OMIM
CCDS CCDS16862
HPRD
IMGT
EMBL AK133794 BC032209 BC035283
GenPept AAH32209 AAH35283 BAE21845

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca