Version 5.4
Mus musculus Protein: Cr2
Summary
InnateDB Protein IDBP-209391.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cr2
Protein Name complement receptor 2
Synonyms C3DR; CD21; CD35; Cr-1; Cr-2; Cr1;
Species Mus musculus
Ensembl Protein ENSMUSP00000080938
InnateDB Gene IDBG-209389 (Cr2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 1 [view]
Protein-DNA 11 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001848 complement binding
GO:0003677 DNA binding
GO:0004872 receptor activity
GO:0004875 complement receptor activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0002430 complement receptor mediated signaling pathway
GO:0030183 B cell differentiation
GO:0042100 B cell proliferation
GO:0042113 B cell activation
Cellular Component
GO:0009897 external side of plasma membrane
GO:0043235 receptor complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:88489
InterPro IPR000436 Sushi/SCR/CCP
PFAM PF00084
PRINTS
PIRSF
SMART SM00032
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9DC83
UniProt Splice Variant
Entrez Gene 12902
UniGene Mm.401997
RefSeq NP_031784
MGI ID
MGI Symbol Cr2
OMIM
CCDS CCDS15642
HPRD
IMGT
EMBL AC139206 AK003072 AK007487 BC109344
GenPept AAI09345 BAB22548 BAB25063

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca