InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sbk1

Summary

InnateDB Protein

IDBP-209427.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sbk1

Protein Name

SH3-binding kinase 1

Synonyms

Sbk;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000060907

InnateDB Gene

IDBG-209425 (Sbk1)

Protein Structure

UniProt Annotation

Function

May be involved in signal-transduction pathways related to the control of brain development. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0007420	brain development
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:2135937

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR016234 Serine/threonine-protein kinase, Sbk1
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

PIRSF000566

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References