InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Spns1

Summary

InnateDB Protein

IDBP-209454.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Spns1

Protein Name

spinster homolog 1 (Drosophila)

Synonyms

2210013K02Rik; Spin1; Spinl;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032994

InnateDB Gene

IDBG-209452 (Spns1)

Protein Structure

UniProt Annotation

Function

Sphingolipid transporter. May be involved in necrotic or autophagic cell death (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0022857	transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0006869	lipid transport
GO:0008150	biological_process
GO:0055085	transmembrane transport

Cellular Component

GO:0005743	mitochondrial inner membrane
GO:0005765	lysosomal membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1920908

InterPro

IPR004156 Organic anion transporter polypeptide OATP
IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain

PFAM

PF03137
PF00083
PF07690

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8R0G7

PhosphoSite