Version 5.4
Mus musculus Protein: B4galnt2
Summary
InnateDB Protein IDBP-209725.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B4galnt2
Protein Name beta-1,4-N-acetyl-galactosaminyl transferase 2
Synonyms AI593864; Dlb-1; Dlb1; Galg2; Galgt2; Ggm3; Igf2bp1;
Species Mus musculus
Ensembl Protein ENSMUSP00000037239
InnateDB Gene IDBG-209723 (B4galnt2)
Protein Structure
UniProt Annotation
Function Responsible for synthesis of murine T-lymphocyte CT antigen. Can add to the low molecular weight acceptor 3'-sialyl-N- acetyllactosamine, to form a non-reducing terminal tetrasaccharide structure.
Subcellular Localization Golgi apparatus membrane; Single-pass type II membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008376 acetylgalactosaminyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
Biological Process
GO:0006047 UDP-N-acetylglucosamine metabolic process
GO:0006486 protein glycosylation
GO:0019276 UDP-N-acetylgalactosamine metabolic process
GO:0022408 negative regulation of cell-cell adhesion
GO:0030259 lipid glycosylation
Cellular Component
GO:0030173 integral component of Golgi membrane
Protein Structure and Domains
PDB ID MGI:1342058
InterPro IPR001173 Glycosyltransferase 2-like
IPR011143 Ganglioside GM2 synthase
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00535
PRINTS
PIRSF PIRSF000474
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q09199
PhosphoSite PhosphoSite-Q09199
TrEMBL A2A615
UniProt Splice Variant
Entrez Gene 14422
UniGene Mm.340702
RefSeq NP_032107
MGI ID
MGI Symbol B4galnt2
OMIM
CCDS CCDS25285
HPRD
IMGT
EMBL AL593858 AL606704 BC139165 BC139166 CH466556 EF372924 L30104
GenPept AAA39802 AAI39166 AAI39167 ABV24439 CAM15505 EDL16003

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca