InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Aldoa

Summary

InnateDB Protein

IDBP-209849.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aldoa

Protein Name

aldolase A, fructose-bisphosphate

Synonyms

Aldo-1; Aldo1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032934

InnateDB Gene

IDBG-209847 (Aldoa)

Protein Structure

UniProt Annotation

Function

Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	22 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	45 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004332	fructose-bisphosphate aldolase activity

Biological Process

GO:0001666	response to hypoxia
GO:0006096	glycolytic process
GO:0009408	response to heat
GO:0032496	response to lipopolysaccharide
GO:0035094	response to nicotine
GO:0043627	response to estrogen
GO:0051289	protein homotetramerization