InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Qprt

Summary

InnateDB Protein

IDBP-210056.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Qprt

Protein Name

quinolinate phosphoribosyltransferase

Synonyms

2410027J01Rik; AI647766; QPRTase;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032912

InnateDB Gene

IDBG-210054 (Qprt)

Protein Structure

UniProt Annotation

Function

Involved in the catabolism of quinolinic acid (QA). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0016763	transferase activity, transferring pentosyl groups
GO:0042803	protein homodimerization activity

Biological Process

GO:0009435	NAD biosynthetic process
GO:0019363	pyridine nucleotide biosynthetic process
GO:0034213	quinolinate catabolic process
GO:0046874	quinolinate metabolic process
GO:0051259	protein oligomerization

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:1914625

InterPro

IPR002638 Quinolinate phosphoribosyl transferase, C-terminal
IPR004393 Nicotinate-nucleotide pyrophosphorylase
IPR022412 Quinolinate phosphoribosyl transferase, N-terminal

PFAM

PF01729
PF02749

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91X91

PhosphoSite