InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pnpo

Summary

InnateDB Protein

IDBP-210077.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pnpo

Protein Name

pyridoxine 5'-phosphate oxidase

Synonyms

AI415282;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018803

InnateDB Gene

IDBG-210075 (Pnpo)

Protein Structure

UniProt Annotation

Function

Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004733	pyridoxamine-phosphate oxidase activity
GO:0010181	FMN binding
GO:0016491	oxidoreductase activity
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors

Biological Process

GO:0008615	pyridoxine biosynthetic process
GO:0042823	pyridoxal phosphate biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005575	cellular_component
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2144151

InterPro

IPR000659 Pyridoxamine 5\'-phosphate oxidase
IPR011576 Pyridoxamine 5\'-phosphate oxidase-like, FMN-binding domain
IPR012349 FMN-binding split barrel
IPR019576 Pyridoxine 5\'-phosphate oxidase, dimerisation, C-terminal

PFAM

PF01243
PF10590

PRINTS

PIRSF

PIRSF000190

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91XF0