Version 5.4
Mus musculus Protein: Commd7
Summary
InnateDB Protein IDBP-210115.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Commd7
Protein Name COMM domain containing 7
Synonyms 2310010I22Rik; AW060956; mU3;
Species Mus musculus
Ensembl Protein ENSMUSP00000071752
InnateDB Gene IDBG-210113 (Commd7)
Protein Structure
UniProt Annotation
Function Associates with the NF-kappa-B complex and suppresses its transcriptional activity. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051059 NF-kappaB binding
Biological Process
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005575 cellular_component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1914197
InterPro IPR009886 HCaRG
PFAM PF07258
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BG94
PhosphoSite PhosphoSite-
TrEMBL Q56A13
UniProt Splice Variant
Entrez Gene 99311
UniGene Mm.294478
RefSeq NP_598611
MGI ID
MGI Symbol Commd7
OMIM
CCDS CCDS16912
HPRD
IMGT
EMBL AK009274 AK078774 AK164805 AL929021 BC003310 BC092215 BC094216
GenPept AAH03310 AAH92215 AAH94216 BAC25249 BAC37387 BAE37928

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca