Version 5.4
Mus musculus Protein: Pip4k2b
Summary
InnateDB Protein IDBP-210316.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pip4k2b
Protein Name phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Synonyms AI848124; c11; PI5P4Kbeta; Pip5k2b;
Species Mus musculus
Ensembl Protein ENSMUSP00000018691
InnateDB Gene IDBG-210314 (Pip4k2b)
Protein Structure
UniProt Annotation
Function Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Associated with the plasma membrane and the endoplasmic reticulum. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016307 phosphatidylinositol phosphate kinase activity
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity
Biological Process
GO:0046488 phosphatidylinositol metabolic process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1934234
InterPro IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
PFAM PF01504
PRINTS
PIRSF
SMART SM00330
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80XI4
PhosphoSite PhosphoSite-Q80XI4
TrEMBL Q91XU2
UniProt Splice Variant
Entrez Gene 108083
UniGene Mm.39700
RefSeq NP_473392
MGI ID
MGI Symbol Pip4k2b
OMIM
CCDS CCDS25329
HPRD
IMGT
EMBL AB054987 AK146559 AY050219 BC047282 CH466556
GenPept AAH47282 AAL18245 BAB62148 BAE27260 EDL16094

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca