Version 5.4
Mus musculus Protein: Orai3
Summary
InnateDB Protein IDBP-210364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Orai3
Protein Name ORAI calcium release-activated calcium modulator 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000050279
InnateDB Gene IDBG-210362 (Orai3)
Protein Structure
UniProt Annotation
Function Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002115 store-operated calcium entry
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3039586
InterPro IPR012446 Calcium release-activated calcium channel protein
PFAM PF07856
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P8G8
PhosphoSite PhosphoSite-Q6P8G8
TrEMBL A3KCG3
UniProt Splice Variant
Entrez Gene 269999
UniGene Mm.437207
RefSeq NP_940816
MGI ID
MGI Symbol Orai3
OMIM
CCDS CCDS21878
HPRD
IMGT
EMBL AB271216 AK136955 AM712358 BC061259 CH466531
GenPept AAH61259 BAE23186 BAF47907 CAN36429 EDL17583

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca