InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Stard3

Summary

InnateDB Protein

IDBP-210558.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Stard3

Protein Name

START domain containing 3

Synonyms

es64; Mln64;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018311

InnateDB Gene

IDBG-210556 (Stard3)

Protein Structure

UniProt Annotation

Function

Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain (By similarity). {ECO:0000250}.

Subcellular Localization

Late endosome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000255PROSITE-ProRule:PRU00770}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008289	lipid binding
GO:0015485	cholesterol binding
GO:0017127	cholesterol transporter activity

Biological Process

GO:0006701	progesterone biosynthetic process
GO:0030301	cholesterol transport

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005765	lysosomal membrane
GO:0005768	endosome
GO:0005770	late endosome
GO:0016021	integral component of membrane
GO:0031902	late endosome membrane

Protein Structure and Domains

PDB ID

MGI:1929618

InterPro

IPR000799 Steroidogenic acute regulatory protein
IPR002913 START domain
IPR019498 MENTAL domain

PFAM

PF01852
PF10457

PRINTS

PR00978

PIRSF

SMART

SM00234

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q61542

PhosphoSite

PhosphoSite-Q61542

TrEMBL

Q544C3

UniProt Splice Variant

Entrez Gene

59045

UniGene

Mm.397760

RefSeq

NP_067522

MGI ID

MGI Symbol

Stard3

OMIM

CCDS

CCDS25345

HPRD

IMGT

EMBL

AK041538 AK155124 BC003313 CH466556 X82457

GenPept

AAH03313 BAC30977 BAE33063 CAA57834 EDL16135