Version 5.4
Mus musculus Protein: Pgap3
Summary
InnateDB Protein IDBP-210583.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pgap3
Protein Name post-GPI attachment to proteins 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000088337
InnateDB Gene IDBG-210579 (Pgap3)
Protein Structure
UniProt Annotation
Function Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Mainly localizes to Golgi apparatus. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006505 GPI anchor metabolic process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID MGI:2444461
InterPro IPR007217 Per1-like
PFAM PF04080
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2A559
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 320655
UniGene Mm.86519
RefSeq NP_001028709
MGI ID
MGI Symbol Pgap3
OMIM
CCDS CCDS25348
HPRD
IMGT
EMBL AK170817 AL591390
GenPept BAE42049 CAM22011 CAM22012

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca