InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psmd3

Summary

InnateDB Protein

IDBP-210722.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Psmd3

Protein Name

proteasome (prosome, macropain) 26S subunit, non-ATPase, 3

Synonyms

AI255837; AntP91a; D11Bwg1349e; Psd3; Tstap91a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000017365

InnateDB Gene

IDBG-210720 (Psmd3)

Protein Structure

UniProt Annotation

Function

Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	4 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	62 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030234	enzyme regulator activity

Biological Process

GO:0042176	regulation of protein catabolic process
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0000502	proteasome complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005838	proteasome regulatory particle
GO:0016020	membrane
GO:0022624	proteasome accessory complex
GO:0070062	extracellular vesicular exosome