Version 5.4
Mus musculus Protein: Ergic3
Summary
InnateDB Protein IDBP-210766.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ergic3
Protein Name ERGIC and golgi 3
Synonyms 2310015B14Rik; AV318804; CGI-54; D2Ucla1; NY-BR-84; Sdbcag84;
Species Mus musculus
Ensembl Protein ENSMUSP00000086025
InnateDB Gene IDBG-210764 (Ergic3)
Protein Structure
UniProt Annotation
Function Possible role in transport between endoplasmic reticulum and Golgi. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269PubMed:12663859}; Multi-pass membrane protein {ECO:0000269PubMed:12663859}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269PubMed:12663859}; Multi- pass membrane protein {ECO:0000269PubMed:12663859}. Endoplasmic reticulum membrane {ECO:0000269PubMed:12663859}; Multi-pass membrane protein {ECO:0000269PubMed:12663859}. Note=Cycles between the endoplasmic reticulum and the Golgi.
Disease Associations
Tissue Specificity Expression is particularly strong in liver, kidney and brain but is almost undetectable in heart. {ECO:0000269PubMed:12663859}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Protein Structure and Domains
PDB ID MGI:1913616
InterPro IPR012936 Endoplasmic reticulum vesicle transporter, C-terminal
PFAM PF07970
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CQE7
PhosphoSite PhosphoSite-Q9CQE7
TrEMBL
UniProt Splice Variant
Entrez Gene 66366
UniGene Mm.467380
RefSeq
MGI ID
MGI Symbol Ergic3
OMIM
CCDS
HPRD
IMGT
EMBL AK009350 AK013942 AK050285 AL833786 BC043720 BC057130
GenPept AAH43720 AAH57130 BAB26233 BAB29073 BAC34166 CAX15725

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca