InnateDB Protein
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IDBP-210796.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Spag4
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Protein Name
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sperm associated antigen 4
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000036484
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InnateDB Gene
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IDBG-210794 (Spag4)
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Protein Structure
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Function |
May assist the organization and assembly of outer dense fibers (ODFs), a specific structure of the sperm tail.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000250}.Isoform 1: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250}. Note=In spermatids, isoform 1 is localized in the transient manchette and in the axoneme of elongating spermatids and epididymal sperm. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Isoform 1 is testis specific and is exclusively expressed in spermatids. {ECO:0000269PubMed:10373309}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2444120
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InterPro |
IPR008979
Galactose-binding domain-like
IPR012919
Sad1/UNC-like, C-terminal
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PFAM |
PF07738
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9JJF2
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q3B7Z4
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UniProt Splice Variant |
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Entrez Gene |
245865
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UniGene |
Mm.404739
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RefSeq |
NP_631890
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MGI ID |
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MGI Symbol |
Spag4
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OMIM |
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CCDS |
CCDS50777
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HPRD |
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IMGT |
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EMBL |
AB041554
AL833786
BB610287
BC107321
BU937622
CA466584
CH466551
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GenPept |
AAI07322
BAA95039
CAM46026
EDL06167
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