Version 5.4
Mus musculus Protein: Krt25
Summary
InnateDB Protein IDBP-210975.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt25
Protein Name keratin 25
Synonyms 4631426H08Rik; Ka38; Krt25a; mIRSa1;
Species Mus musculus
Ensembl Protein ENSMUSP00000048439
InnateDB Gene IDBG-210973 (Krt25)
Protein Structure
UniProt Annotation
Function Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). {ECO:0000269PubMed:14996088, ECO:0000269PubMed:17920809}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:14996088}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0007568 aging
GO:0031069 hair follicle morphogenesis
GO:0042633 hair cycle
GO:0045109 intermediate filament organization
Cellular Component
GO:0005737 cytoplasm
GO:0005882 intermediate filament
Protein Structure and Domains
PDB ID MGI:1918060
InterPro IPR001664 Intermediate filament protein
IPR002957 Keratin, type I
PFAM PF00038
PRINTS PR01248
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VCW2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 70810
UniGene Mm.268173
RefSeq NP_598491
MGI ID
MGI Symbol Krt25
OMIM
CCDS CCDS25377
HPRD
IMGT
EMBL AL590991 BC018391
GenPept AAH18391 CAM18789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca