InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hmx2

Summary

InnateDB Protein

IDBP-211010.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hmx2

Protein Name

H6 homeobox 2

Synonyms

Nkx-5.2; Nkx5-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000058205

InnateDB Gene

IDBG-211008 (Hmx2)

Protein Structure

UniProt Annotation

Function

Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. {ECO:0000269PubMed:11748138, ECO:0000269PubMed:15363417}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in the developing CNS, including a specific expression in vestibular structures throughout inner ear development. {ECO:0000269PubMed:11748138}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007420	brain development
GO:0008284	positive regulation of cell proliferation
GO:0030154	cell differentiation
GO:0042472	inner ear morphogenesis