Mus musculus Protein: Gpr26
Summary
InnateDB Protein IDBP-211033.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr26
Protein Name G protein-coupled receptor 26
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000041664
InnateDB Gene IDBG-211031 (Gpr26)
Protein Structure
UniProt Annotation
Function Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Exclusively expressed in the brain. Prominent expression is detected throughout the entire neocortex at all rostrocaudal and dorsoventral levels. Strong expression is detected in olfactory and auditory sensory areas. {ECO:0000269PubMed:17363172}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2441758
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019427 7TM GPCR, serpentine receptor class w (Srw)
PFAM PF00001
PF10320
PF10324
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BZA7
PhosphoSite PhosphoSite-
TrEMBL Q0VBG4
UniProt Splice Variant
Entrez Gene 233919
UniGene Mm.252519
RefSeq NP_775586
MGI ID
MGI Symbol Gpr26
OMIM
CCDS CCDS21920
HPRD
IMGT
EMBL AK036100 AK042755 AY255585 BC119380 BC120647 CH466531
GenPept AAI19381 AAI20648 AAO85097 BAC29305 BAC31354 EDL17721