InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cpxm2

Summary

InnateDB Protein

IDBP-211047.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cpxm2

Protein Name

carboxypeptidase X 2 (M14 family)

Synonyms

4632435C11Rik; CPX-2; Cpx2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033149

InnateDB Gene

IDBG-211045 (Cpxm2)

Protein Structure

UniProt Annotation

Function

May be involved in cell-cell interactions.

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Highly expressed in lung and kidney. Moderate expression in liver and brain, including the cerebral cortex, piriform cortex, nucleus of the lateral olfactory tract, hippocampus, habenular nucleus, and choroid plexus. {ECO:0000269PubMed:9809751}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004181	metallocarboxypeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0007155	cell adhesion

Cellular Component

GO:0005615	extracellular space
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

MGI:1926006

InterPro

IPR000421 Coagulation factor 5/8 C-terminal type domain
IPR000834 Peptidase M14, carboxypeptidase A
IPR008969 Carboxypeptidase-like, regulatory domain
IPR008979 Galactose-binding domain-like

PFAM

PF00754
PF00246

PRINTS

PR00765

PIRSF

SMART

SM00231
SM00631

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt