Version 5.4
Mus musculus Protein: Eif1
Summary
InnateDB Protein IDBP-211325.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif1
Protein Name eukaryotic translation initiation factor 1
Synonyms Sui1-rs1;
Species Mus musculus
Ensembl Protein ENSMUSP00000041538
InnateDB Gene IDBG-211323 (Eif1)
Protein Structure
UniProt Annotation
Function Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003743 translation initiation factor activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006413 translational initiation
GO:0009048 dosage compensation by inactivation of X chromosome
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:105125
InterPro IPR001950 Translation initiation factor SUI1
IPR005874 Eukaryotic translation initiation factor SUI1
PFAM PF01253
PRINTS
PIRSF PIRSF004499
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48024
PhosphoSite PhosphoSite-P48024
TrEMBL Q4V9T8
UniProt Splice Variant
Entrez Gene 432950
UniGene Mm.450756
RefSeq NP_035638
MGI ID
MGI Symbol Eif1
OMIM
CCDS CCDS25417
HPRD
IMGT
EMBL AF129888 AK148032 AK151070 AK151575 AK152194 AK169763 BC003463 BC010791 BC081429 BC096656 BC096691 CH466662 Z50159
GenPept AAD31266 AAH03463 AAH10791 AAH81429 AAH96656 AAH96691 BAE28300 BAE30086 BAE30515 BAE31024 BAE41352 CAA90519 EDL02569

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca