Version 5.4
Mus musculus Protein: Ctnnbl1
Summary
InnateDB Protein IDBP-211330.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ctnnbl1
Protein Name catenin, beta like 1
Synonyms 5730471K09Rik; NAP; NYD-SP19; P14L;
Species Mus musculus
Ensembl Protein ENSMUSP00000029178
InnateDB Gene IDBG-211326 (Ctnnbl1)
Protein Structure
UniProt Annotation
Function Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May induce apoptosis (By similarity). Participates in AID/AICDA-mediated Ig class switching recombination (CSR). {ECO:0000250, ECO:0000269PubMed:20585033}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0006915 apoptotic process
GO:0016445 somatic diversification of immunoglobulins
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1913892
InterPro IPR013180 Beta-catenin-like protein 1, N-terminal
IPR016024 Armadillo-type fold
PFAM PF08216
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CWL8
PhosphoSite PhosphoSite-Q9CWL8
TrEMBL
UniProt Splice Variant
Entrez Gene 66642
UniGene Mm.45193
RefSeq NP_079956
MGI ID
MGI Symbol Ctnnbl1
OMIM
CCDS CCDS16982
HPRD
IMGT
EMBL AK010547 AK044690 AK077616 AK145598 AK145719 AY009405 BC050787
GenPept AAH50787 AAK27389 BAB27020 BAC32034 BAC36902 BAE26532 BAE26609

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca