Version 5.4
Mus musculus Protein: Klhl11
Summary
InnateDB Protein IDBP-211430.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klhl11
Protein Name kelch-like 11 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000054963
InnateDB Gene IDBG-211428 (Klhl11)
Protein Structure
UniProt Annotation
Function Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2388648
InterPro IPR000210 BTB/POZ-like
IPR006652 Kelch repeat type 1
IPR011333 BTB/POZ fold
IPR011705 BTB/Kelch-associated
IPR013069 BTB/POZ
PFAM PF01344
PF07707
PF00651
PRINTS
PIRSF
SMART SM00225
SM00612
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CE33
PhosphoSite PhosphoSite-Q8CE33
TrEMBL Q14DU1
UniProt Splice Variant
Entrez Gene 217194
UniGene Mm.413305
RefSeq NP_766153
MGI ID
MGI Symbol Klhl11
OMIM
CCDS CCDS25424
HPRD
IMGT
EMBL AK029101 AK169910 BC011167 BC111873 CH466662
GenPept AAH11167 AAI11874 BAC26297 BAE41452 EDL02557

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca