Version 5.4
Mus musculus Protein: Adig
Summary
InnateDB Protein IDBP-211522.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adig
Protein Name adipogenin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000051732
InnateDB Gene IDBG-211520 (Adig)
Protein Structure
UniProt Annotation
Function Plays a role in stimulating adipocyte differentiation and development. {ECO:0000269PubMed:16132694}.
Subcellular Localization Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000269PubMed:15567149, ECO:0000269PubMed:16132694}.
Disease Associations
Tissue Specificity Selectively expressed in adipose tissue where it is particularly enriched in brown adipose tissue. In adipose tissue, expressed exclusively in adipocytes and not in the stromal-vascular cell population. Expressed at much lower levels in heart, stomach and muscle and barely detected in kidney and lung. {ECO:0000269PubMed:15567149, ECO:0000269PubMed:16132694}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007283 spermatogenesis
GO:0045600 positive regulation of fat cell differentiation
GO:0050872 white fat cell differentiation
GO:0050873 brown fat cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2675492
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R400
PhosphoSite PhosphoSite-Q8R400
TrEMBL
UniProt Splice Variant
Entrez Gene 246747
UniGene
RefSeq NP_663610
MGI ID
MGI Symbol Adig
OMIM
CCDS CCDS16990
HPRD
IMGT
EMBL AK131610 AL663091 AY092026 BC054059 DQ223719
GenPept AAH54059 AAM12949 ABB18023 BAE20719 CAM23057

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca