InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc32a1

Summary

InnateDB Protein

IDBP-211531.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc32a1

Protein Name

solute carrier family 32 (GABA vesicular transporter), member 1

Synonyms

R75019; VGAT; Viaat;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000036299

InnateDB Gene

IDBG-211529 (Slc32a1)

Protein Structure

UniProt Annotation

Function

Involved in the uptake of GABA and glycine into the synaptic vesicles.

Subcellular Localization

Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Brain and retina. Localized in horizontal cell tips at both rod and cone terminals. {ECO:0000269PubMed:12115694}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015187	glycine transmembrane transporter activity
GO:0015495	gamma-aminobutyric acid:hydrogen symporter activity

Biological Process

GO:0006836	neurotransmitter transport
GO:0007568	aging
GO:0015812	gamma-aminobutyric acid transport
GO:0015816	glycine transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0008021	synaptic vesicle
GO:0030425	dendrite
GO:0030659	cytoplasmic vesicle membrane
GO:0043005	neuron projection
GO:0043229	intracellular organelle
GO:0044292	dendrite terminus
GO:0044306	neuron projection terminus
GO:0044316	cone cell pedicle
GO:0045202	synapse
GO:0051286	cell tip
GO:0060077	inhibitory synapse