Mus musculus Protein: Lpin3
Summary
InnateDB Protein IDBP-211664.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lpin3
Protein Name lipin 3
Synonyms 9130206L11Rik; AA438110; AV236139; mKIAA4023;
Species Mus musculus
Ensembl Protein ENSMUSP00000043053
InnateDB Gene IDBG-211662 (Lpin3)
Protein Structure
UniProt Annotation
Function Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Significant expression in intestine and other regions of the gastrointestinal tract. {ECO:0000269PubMed:17158099}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008195 phosphatidate phosphatase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0016311 dephosphorylation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1891342
InterPro IPR007651 Lipin, N-terminal
IPR013209 LNS2, Lipin/Ned1/Smp2
IPR023214 HAD-like domain
PFAM PF04571
PF08235
PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART SM00775
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99PI4
PhosphoSite PhosphoSite-Q99PI4
TrEMBL Q571G1
UniProt Splice Variant
Entrez Gene 64899
UniGene Mm.488657
RefSeq NP_001186047
MGI ID
MGI Symbol Lpin3
OMIM
CCDS CCDS16998
HPRD
IMGT
EMBL AF286724 AK049363 AK163833 AK220228 BC117882 BC117883 CH466551
GenPept AAG52762 AAI17883 AAI17884 BAC33710 BAD90153 BAE37510 EDL06298