InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mybl2

Summary

InnateDB Protein

IDBP-211839.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mybl2

Protein Name

myeloblastosis oncogene-like 2

Synonyms

B-Myb; Bmyb;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018005

InnateDB Gene

IDBG-211837 (Mybl2)

Protein Structure

UniProt Annotation

Function

Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	8 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0090307	spindle assembly involved in mitosis