Version 5.4
Mus musculus Protein: Serinc3
Summary
InnateDB Protein IDBP-211928.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serinc3
Protein Name serine incorporator 3
Synonyms AA959945; AA960047; AIGP1; DIFF33; Tde1; TMS-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000017851
InnateDB Gene IDBG-211926 (Serinc3)
Protein Structure
UniProt Annotation
Function May be involved in cellular transformation. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:12486168}; Multi-pass membrane protein {ECO:0000269PubMed:12486168}. Golgi apparatus membrane {ECO:0000269PubMed:12486168}; Multi-pass membrane protein {ECO:0000269PubMed:12486168}.
Disease Associations
Tissue Specificity Highly expressed in the neuronal populations such as Purkinje cells in the cerebellum, brainstem and spinal motor neurons, locus coeruleus and raphe nuclei. Highly expressed also in thymus, kidney liver and testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:1902237 positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1349457
InterPro IPR005016 TMS membrane protein/tumour differentially expressed protein
PFAM PF03348
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZI9
PhosphoSite PhosphoSite-Q9QZI9
TrEMBL
UniProt Splice Variant
Entrez Gene 26943
UniGene Mm.413315
RefSeq NP_036162
MGI ID
MGI Symbol Serinc3
OMIM
CCDS CCDS17013
HPRD
IMGT
EMBL AB029499 AB078029 AF181684 AK031101 AK150106 AK152720 AK155921 AK159347 AK159819 AK160005 AK160055 AK161981 AK164807 AK166924 AK170350 BC011295 BC022901 BC029026 L29441
GenPept AAA74236 AAD54420 AAH11295 AAH22901 AAH29026 BAC05511 BAC27253 BAC44828 BAE29313 BAE31443 BAE33504 BAE35009 BAE35399 BAE35553 BAE35593 BAE36664 BAE37929 BAE39119 BAE41738

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca