Version 5.4
Mus musculus Protein: Ifitm5
Summary
InnateDB Protein IDBP-211933.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ifitm5
Protein Name interferon induced transmembrane protein 5
Synonyms 1110003J06Rik; AW213665; Bril; DSPA1; Hrmp1; Hrtm1;
Species Mus musculus
Ensembl Protein ENSMUSP00000026562
InnateDB Gene IDBG-211931 (Ifitm5)
Protein Structure
UniProt Annotation
Function Plays a role in bone mineralization. {ECO:0000269PubMed:18442316}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:18442316}; Multi-pass membrane protein {ECO:0000269PubMed:18442316}.
Disease Associations
Tissue Specificity Highly expressed in osteoblasts of adults and embryos. Expressed in primitive hemopoietic cells. {ECO:0000269PubMed:11106657, ECO:0000269PubMed:18442316}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007275 multicellular organismal development
GO:0009607 response to biotic stimulus
GO:0030282 bone mineralization
GO:0030500 regulation of bone mineralization
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1934923
InterPro IPR007593 CD225/Dispanin family
PFAM PF04505
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88728
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 73835
UniGene Mm.389989
RefSeq NP_444318
MGI ID
MGI Symbol Ifitm5
OMIM
CCDS CCDS21993
HPRD
IMGT
EMBL AJ009781 BC103790 BK001124 CH466531 EU380257 FJ200451
GenPept AAI03791 ABZ85873 ACI26732 CAA08829 DAA01239 EDL17974

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca