InnateDB Protein
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IDBP-211990.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ano9
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Protein Name
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anoctamin 9
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Synonyms
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5430425C04Rik; Tmem16j; Tp53i5; Trp53i5;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000067689
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InnateDB Gene
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IDBG-211988 (Ano9)
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Protein Structure
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|
Function |
Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane; Multi-pass membrane protein. Note=Shows predominantly an intracellular localization with a weak expression in the cell membrane. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Predominant expression seen in epithelial tissues. {ECO:0000269PubMed:20056604}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
0
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Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0005229
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intracellular calcium activated chloride channel activity
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GO:0017128
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phospholipid scramblase activity
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Biological Process |
GO:0006821
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chloride transport
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GO:0061589
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calcium activated phosphatidylserine scrambling
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GO:0061590
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calcium activated phosphatidylcholine scrambling
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GO:0061591
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calcium activated galactosylceramide scrambling
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GO:1902476
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chloride transmembrane transport
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GO:1902939
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negative regulation of intracellular calcium activated chloride channel activity
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Cellular Component |
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PDB ID |
MGI:1918595
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InterPro |
IPR007632
Anoctamin
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PFAM |
PF04547
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P86044
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PhosphoSite |
PhosphoSite-P86044
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
71345
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UniGene |
Mm.235813
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RefSeq |
NP_848468
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MGI ID |
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MGI Symbol |
Ano9
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OMIM |
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CCDS |
CCDS52438
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HPRD |
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IMGT |
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EMBL |
AC109272
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GenPept |
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