InnateDB Protein
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IDBP-212046.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Coa3
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Protein Name
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coiled-coil domain containing 56
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Synonyms
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1810033A19Rik; Ccdc56; D11Ertd99e; HSPC009;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000017332
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InnateDB Gene
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IDBG-212044 (Coa3)
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Protein Structure
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Function |
Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
11 [view]
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|
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Molecular Function |
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Biological Process |
GO:0033617
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mitochondrial respiratory chain complex IV assembly
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GO:0070131
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positive regulation of mitochondrial translation
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Cellular Component |
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PDB ID |
MGI:1098757
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InterPro |
IPR018628
Coiled-coil domain-containing protein 56
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PFAM |
PF09813
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D2R6
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PhosphoSite |
PhosphoSite-Q9D2R6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
52469
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UniGene |
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RefSeq |
NP_080894
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MGI ID |
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MGI Symbol |
Coa3
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OMIM |
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CCDS |
CCDS25460
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HPRD |
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IMGT |
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EMBL |
AK019025
AL590969
BC026206
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GenPept |
AAH26206
BAB31515
CAM19561
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