Mus musculus Protein: Wfdc12
Summary
InnateDB Protein IDBP-212049.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wfdc12
Protein Name WAP four-disulfide core domain 12
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000050836
InnateDB Gene IDBG-212047 (Wfdc12)
Protein Structure
UniProt Annotation
Function Antibacterial protein which inhibits the growth of E.coli and S.aureus. Putative acid-stable proteinase inhibitor. {ECO:0000250UniProtKB:Q8WWY7, ECO:0000269PubMed:12574366}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Constitutively expressed in tongue. {ECO:0000269PubMed:12574366}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0042742 defense response to bacterium
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:2183434
InterPro IPR008197 Whey acidic protein-type 4-disulphide core
PFAM PF00095
PRINTS PR00003
PIRSF
SMART SM00217
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JHY3
PhosphoSite PhosphoSite-Q9JHY3
TrEMBL Q3V469
UniProt Splice Variant
Entrez Gene 192200
UniGene
RefSeq NP_619625
MGI ID
MGI Symbol Wfdc12
OMIM
CCDS CCDS38318
HPRD
IMGT
EMBL AF276975 AF482010 AK008999 BC030939
GenPept AAF86472 AAH30939 AAL90748 BAE20421