Homo sapiens Protein: RCOR1
Summary
InnateDB Protein IDBP-21218.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCOR1
Protein Name REST corepressor 1
Synonyms COREST; RCOR;
Species Homo sapiens
Ensembl Protein ENSP00000262241
InnateDB Gene IDBG-21216 (RCOR1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 75 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 75 [view]
Protein-Protein 72 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0007596 blood coagulation
GO:0016032 viral process
GO:0045087 innate immune response (InnateDB)
GO:0045892 negative regulation of transcription, DNA-templated
GO:0070933 histone H4 deacetylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0017053 transcriptional repressor complex
Protein Structure and Domains
PDB ID
InterPro IPR000104 Antifreeze protein, type I
IPR000949 ELM2 domain
IPR001005 SANT/Myb domain
IPR009057 Homeodomain-like
PFAM PF01448
PF00249
PRINTS PR00308
PIRSF
SMART SM00717
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKL0
PhosphoSite PhosphoSite-Q9UKL0
TrEMBL J3KN32
UniProt Splice Variant
Entrez Gene 23186
UniGene Hs.626437
RefSeq NP_055971
HUGO HGNC:17441
OMIM 607675
CCDS CCDS9974
HPRD 09645
IMGT
EMBL AF155595 AL132801 AL136293 BC051003 BC064495 CH471061 D31888
GenPept AAF01498 AAH51003 AAH64495 BAA06686 EAW81793