Version 5.4
Mus musculus Protein: Chid1
Summary
InnateDB Protein IDBP-212313.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chid1
Protein Name chitinase domain containing 1
Synonyms 3110023E09Rik; AI841869;
Species Mus musculus
Ensembl Protein ENSMUSP00000026586
InnateDB Gene IDBG-212311 (Chid1)
Protein Structure
UniProt Annotation
Function Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro) (By similarity). {ECO:0000250}.
Subcellular Localization Secreted. Lysosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004568 chitinase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
GO:0005764 lysosome
Protein Structure and Domains
PDB ID MGI:1915288
InterPro IPR001223 Glycoside hydrolase, family 18, catalytic domain
IPR011583 Chitinase II
IPR017853 Glycoside hydrolase, superfamily
PFAM PF00704
PRINTS
PIRSF
SMART SM00636
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q922Q9
PhosphoSite PhosphoSite-Q922Q9
TrEMBL Q9CRU8
UniProt Splice Variant
Entrez Gene 68038
UniGene Mm.245355
RefSeq NP_080798
MGI ID
MGI Symbol Chid1
OMIM
CCDS CCDS22019
HPRD
IMGT
EMBL AK014071 AK014141 AK050655 AK160156 BC006876 BC061063
GenPept AAH06876 AAH61063 BAB29142 BAB29176 BAC34365 BAE35662

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca