InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Meox1

Summary

InnateDB Protein

IDBP-212396.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Meox1

Protein Name

mesenchyme homeobox 1

Synonyms

AI385561; D330041M02Rik; Mox-1; Mox1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000051158

InnateDB Gene

IDBG-212394 (Meox1)

Protein Structure

UniProt Annotation

Function

Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.

Disease Associations

Tissue Specificity

Heart, lateral plate derivatives, kidney, loose connective tissue at sites of bone formation and skeletal muscle-connective tissue apposition.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding
GO:0071837	HMG box domain binding

Biological Process

GO:0001757	somite specification
GO:0006355	regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter