InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gjc1

Summary

InnateDB Protein

IDBP-212782.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gjc1

Protein Name

gap junction protein, gamma 1

Synonyms

C130009G16Rik; Cnx45; Cx45; Gja-7; Gja7;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000090228

InnateDB Gene

IDBG-212780 (Gjc1)

Protein Structure

UniProt Annotation

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Subcellular Localization

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005243	gap junction channel activity
GO:0005515	protein binding

Biological Process

GO:0001570	vasculogenesis
GO:0007267	cell-cell signaling
GO:0007268	synaptic transmission
GO:0007507	heart development
GO:0007601	visual perception
GO:0034220	ion transmembrane transport
GO:0048468	cell development
GO:0048738	cardiac muscle tissue development