Version 5.4
Mus musculus Protein: Nadsyn1
Summary
InnateDB Protein IDBP-212831.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nadsyn1
Protein Name NAD synthetase 1
Synonyms 9130012B15Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000033415
InnateDB Gene IDBG-212829 (Nadsyn1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Highly expressed in small intestine, kidney, liver and testis. Weakly expressed in skeletal muscle, spleen, lung, heart and brain. {ECO:0000269PubMed:12547821}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0008795 NAD+ synthase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Biological Process
GO:0006807 nitrogen compound metabolic process
GO:0009435 NAD biosynthetic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1926164
InterPro IPR003010 Carbon-nitrogen hydrolase
IPR003694 NAD(+) synthetase
IPR014445 Glutamine-dependent NAD(+) synthetase
IPR022310 NAD/GMP synthase
PFAM PF00795
PF02540
PRINTS
PIRSF PIRSF006630
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q711T7
PhosphoSite PhosphoSite-Q711T7
TrEMBL
UniProt Splice Variant
Entrez Gene 78914
UniGene Mm.446678
RefSeq NP_084497
MGI ID
MGI Symbol Nadsyn1
OMIM
CCDS CCDS22047
HPRD
IMGT
EMBL AJ305343 AJ311612 AK020264 AK041101 AK042389 BC038016
GenPept AAH38016 BAB32048 BAC30822 BAC31247 CAC83797 CAC88023

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca