Version 5.4
Mus musculus Protein: Cttn
Summary
InnateDB Protein IDBP-212884.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Cttn
Protein Name cortactin
Synonyms 1110020L01Rik; Ems1;
Species Mus musculus
Ensembl Protein ENSMUSP00000033407
InnateDB Gene IDBG-212876 (Cttn)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 56 experimentally validated interaction(s) in this database.
They are also associated with 60 interaction(s) predicted by orthology.
Experimentally validated
Total 56 [view]
Protein-Protein 56 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 60 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0001726 ruffle
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005938 cell cortex
GO:0030027 lamellipodium
Protein Structure and Domains
PDB ID MGI:99695
InterPro IPR001452 SH3 domain
IPR003134 Hs1/Cortactin
IPR011511 Variant SH3 domain
PFAM PF00018
PF14604
PF02218
PF07653
PRINTS PR00452
PIRSF
SMART SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q921L6
UniProt Splice Variant
Entrez Gene 13043
UniGene Mm.490123
RefSeq NP_001239501
MGI ID
MGI Symbol Cttn
OMIM
CCDS CCDS57599
HPRD
IMGT
EMBL AC140268 AK165555 AK168945 BC011434 CH466531
GenPept AAH11434 BAE38252 BAE40752 EDL18246

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca