Version 5.4
Homo sapiens Protein: TBC1D21
Summary
InnateDB Protein IDBP-21305.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D21
Protein Name TBC1 domain family, member 21
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000300504
InnateDB Gene IDBG-21303 (TBC1D21)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein for Rab family protein(s).
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0008150 biological_process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0001669 acrosomal vesicle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
PFAM PF00566
PRINTS
PIRSF
SMART SM00164
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IYX1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 161514
UniGene Hs.124512
RefSeq NP_699187
HUGO HGNC:28536
OMIM
CCDS CCDS10252
HPRD 15473
IMGT
EMBL AB449907 AC018943 AC108137 BC033516
GenPept AAH33516 BAH16650

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca