Version 5.4
| Mus musculus Protein: Sppl2c | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-213107.7 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Sppl2c | ||||||||
| Protein Name | RIKEN cDNA 4933407P14 gene | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000091453 | ||||||||
| InnateDB Gene | IDBG-213105 (Sppl2c) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. {ECO:0000250}. | ||||||||
| Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:3045264 | ||||||||
| InterPro |
IPR003137
Protease-associated domain, PA IPR006639 Presenilin/signal peptide peptidase IPR007369 Peptidase A22B, signal peptide peptidase |
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| PFAM |
PF02225
PF04258 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00730
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A2A6C4 | ||||||||
| PhosphoSite | PhosphoSite-A2A6C4 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 237958 | ||||||||
| UniGene | Mm.117063 | ||||||||
| RefSeq | NP_001076004 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Sppl2c | ||||||||
| OMIM | |||||||||
| CCDS | CCDS36351 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK077122 AL596383 BC100418 | ||||||||
| GenPept | AAI00419 BAC36625 CAM21649 | ||||||||