Version 5.4
Mus musculus Protein: Cbln4
Summary
InnateDB Protein IDBP-213274.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cbln4
Protein Name cerebellin 4 precursor protein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000085263
InnateDB Gene IDBG-213272 (Cbln4)
Protein Structure
UniProt Annotation
Function May be involved in synaptic functions in the CNS. May play a role in CBLN3 export from the endoplasmic reticulum and secretion.
Subcellular Localization Secreted. Cell junction, synapse.
Disease Associations
Tissue Specificity Expressed in brain with high levels in particular thalamic nuclei. In the thalamus, predominantly expressed in neurons within the parafascicular nucleus (at protein level). Very low or no expression in most other brain regions. {ECO:0000269PubMed:16930405, ECO:0000269PubMed:22220752}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0009306 protein secretion
Cellular Component
GO:0005615 extracellular space
GO:0030054 cell junction
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:2154433
InterPro IPR001073 Complement C1q protein
IPR008983 Tumour necrosis factor-like domain
PFAM PF00386
PRINTS PR00007
PIRSF
SMART SM00110
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BME9
PhosphoSite PhosphoSite-Q8BME9
TrEMBL
UniProt Splice Variant
Entrez Gene 228942
UniGene Mm.40555
RefSeq NP_783439
MGI ID
MGI Symbol Cbln4
OMIM
CCDS CCDS17126
HPRD
IMGT
EMBL AK032406 AK032621 AY134663 BC094540 BC132025 BC132027 CH466551
GenPept AAH94540 AAI32026 AAI32028 AAN08614 BAC27855 BAC27954 EDL06594

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca