InnateDB Protein
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IDBP-213529.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gm885
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Protein Name
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predicted gene 885
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000083538
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InnateDB Gene
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IDBG-213527 (Gm885)
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Protein Structure
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Function |
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE- mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. {ECO:0000269PubMed:20526344}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:20526344}; Single-pass type I membrane protein {ECO:0000269PubMed:20526344}.Isoform 2: Secreted {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed in myeloid cells (dendritic cells, macrophages and neutrophils but not in T-cells, B-cells or natural killer cells) and mast cells (at protein level). {ECO:0000269PubMed:20526344}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2685731
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InterPro |
IPR003599
Immunoglobulin subtype
IPR007110
Immunoglobulin-like domain
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
SM00409
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TIGRFAMs |
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Modification |
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SwissProt |
Q3TB92
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PhosphoSite |
PhosphoSite-Q3TB92
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TrEMBL |
S4R1V2
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UniProt Splice Variant |
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Entrez Gene |
380732
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UniGene |
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RefSeq |
NP_001028607
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MGI ID |
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MGI Symbol |
Milr1
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OMIM |
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CCDS |
CCDS25560
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HPRD |
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IMGT |
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EMBL |
AB542953
AK136488
AK151814
AK153506
AK169925
AK170947
AK171381
AL603664
BC139224
BC139225
BC145580
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GenPept |
AAI39225
AAI39226
AAI45581
BAE23003
BAE30712
BAE32051
BAE41463
BAE42134
BAE42422
BAJ08254
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