InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psmd12

Summary

InnateDB Protein

IDBP-213694.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Psmd12

Protein Name

proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

Synonyms

1500002F15Rik; AI480719; P55;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021063

InnateDB Gene

IDBG-213692 (Psmd12)

Protein Structure

UniProt Annotation

Function

Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	59 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

Cellular Component

GO:0005838	proteasome regulatory particle
GO:0016020	membrane
GO:0022624	proteasome accessory complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1914247

InterPro

IPR000717 Proteasome component (PCI) domain

PFAM

PF01399

PRINTS

PIRSF

SMART

SM00088

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D8W5

PhosphoSite

PhosphoSite-Q9D8W5

TrEMBL

Q9CSW4

UniProt Splice Variant

Entrez Gene

66997

UniGene

Mm.416023

RefSeq

NP_080170

MGI ID

MGI Symbol

Psmd12

OMIM

CCDS

CCDS25568

HPRD

IMGT

EMBL

AK007619 AK007680 AK009969 AK011806 AK017843 AK151242 AL645687 AL683815 BC004694 CH466558

GenPept

AAH04694 BAB25140 BAB25184 BAB26619 BAB27853 BAB30969 BAE30234 CAM20679 CAM25445 EDL34331