Version 5.4
Homo sapiens Protein: PSPN
Summary
InnateDB Protein IDBP-21375.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSPN
Protein Name persephin
Synonyms PSP;
Species Homo sapiens
Ensembl Protein ENSP00000245810
InnateDB Gene IDBG-21373 (PSPN)
Protein Structure
UniProt Annotation
Function Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007417 central nervous system development
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR001839 Transforming growth factor-beta, C-terminal
IPR029034 Cystine-knot cytokine
PFAM PF00019
PRINTS
PIRSF
SMART SM00204
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60542
PhosphoSite PhosphoSite-O60542
TrEMBL
UniProt Splice Variant
Entrez Gene 5623
UniGene Hs.742105
RefSeq NP_004149
HUGO HGNC:9579
OMIM 602921
CCDS CCDS12164
HPRD 04230
IMGT
EMBL AF040962
GenPept AAC39640

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca