Version 5.4
Mus musculus Protein: Ythdf1
Summary
InnateDB Protein IDBP-213919.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ythdf1
Protein Name YTH domain family 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000037808
InnateDB Gene IDBG-213917 (Ythdf1)
Protein Structure
UniProt Annotation
Function Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
GO:1990247 N6-methyladenosine-containing RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1917431
InterPro IPR007275 YTH domain
PFAM PF04146
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P59326
PhosphoSite PhosphoSite-P59326
TrEMBL Q3U8D6
UniProt Splice Variant
Entrez Gene 228994
UniGene Mm.413406
RefSeq NP_776122
MGI ID
MGI Symbol Ythdf1
OMIM
CCDS CCDS17188
HPRD
IMGT
EMBL AK046768 AK152264 AK168430 AK172582 BC061479 BC065050
GenPept AAH61479 AAH65050 BAC32861 BAE31082 BAE40338 BAE43080

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca