InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Enpp7

Summary

InnateDB Protein

IDBP-214664.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Enpp7

Protein Name

ectonucleotide pyrophosphatase/phosphodiesterase 7

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000090027

InnateDB Gene

IDBG-214662 (Enpp7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004767	sphingomyelin phosphodiesterase activity
GO:0008484	sulfuric ester hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0006684	sphingomyelin metabolic process
GO:0006685	sphingomyelin catabolic process
GO:0008152	metabolic process
GO:0008156	negative regulation of DNA replication
GO:0008285	negative regulation of cell proliferation

Cellular Component

GO:0005794	Golgi apparatus
GO:0005902	microvillus

Protein Structure and Domains

PDB ID

MGI:3027917

InterPro

IPR000917 Sulfatase
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
IPR006124 Metalloenzyme
IPR017850 Alkaline-phosphatase-like, core domain

PFAM

PF00884
PF01663
PF01676

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-